Publications | Epigenetic Memory Lab

2024

Fisher AG. Cell and developmental biology: grand challenges. Front Cell Dev Biol. Mar 15; 12:1377073 (2024). https://doi.org/10.3389/fcell.2024.1377073

Veland, N., Gleneadie, H.J., Brown, K.E. et al. Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung. Commun Biol 7, 442 (2024). https://doi.org/10.1038/s42003-024-06089-6

Prodani, C., Irvine, E.E., Sardini, A. et al. Protein restriction during pregnancy alters Cdkn1c silencing, dopamine circuitry and offspring behaviour without changing expression of key neuronal marker genes. Sci Rep 14, 8528 (2024). https://doi.org/10.1038/s41598-024-59083-7

Dimond, A., Gim, D.H., Ing-Simmons, E. et al. PBK/TOPK mediates Ikaros, Aiolos and CTCF displacement from mitotic chromosomes and alters chromatin accessibility at selected C2H2-zinc finger protein binding sites. bioRxiv (2024). https://doi.org/10.1101/2024.04.23.590758

Buenaventura, T., Bagci, H., Patrascan, I. et al. Competition shapes the landscape of X chromosome-linked genetic diversity. Nat Genet, 56, 1678-1688 (2024). https://doi.org/10.1038/s41588-024-01840-5

Djeghloul, D., Cheriyamkunnel, S., Patel, B. et al. Hbo1 and Msl complexes preserve differential compaction and H3K27me3 marking of active and inactive X chromosomes during mitosis. Research Square (2024). https://doi.org/10.21203/rs.3.rs-4687808/v1

2023

Gleneadie, H.J., Fernandez-Ruiz, B., Sardini, A. et al. Endogenous bioluminescent reporters reveal a sustained increase in utrophin gene expression upon EZH2 and ERK1/2 inhibition. Commun Biol 6, 318 (2023). https://doi.org/10.1038/s42003-023-04666-9

Dimond, A., Van de Pette, M., Taylor-Bateman, V. et al. Drug-induced loss of imprinting revealed using bioluminescent reporters of Cdkn1c. Sci Rep 13, 5626 (2023). https://doi.org/10.1038/s41598-023-32747-6

Fisher, A.G., Merkenschlager, M. Avrion Mitchison (1928–2022). Nat Immunol 24, 559 (2023). https://doi.org/10.1038/s41590-023-01461-w

Djeghloul, D., Dimond, A., Cheriyamkunnel, S. et al. Loss of H3K9 trimethylation alters chromosome compaction and transcription factor retention during mitosis. Nat Struct Mol Biol 30, 489–501 (2023). https://doi.org/10.1038/s41594-023-00943-7

Al-jibury, E., King, J.W.D., Guo, Y. et al. A deep learning method for replicate-based analysis of chromosome conformation contacts using Siamese neural networks. Nat Commun 14, 5007 (2023). https://doi.org/10.1038/s41467-023-40547-9

Gleneadie, H.J., Dimond, A., and Fisher, A.G. Harnessing bioluminescence for drug discovery and epigenetic research. Front. in Drug Discov. 3 (2023). https://www.frontiersin.org/articles/10.3389/fddsv.2023.1249507/full

2022

Van de Pette, M., Dimond, A., Galvão, A.M. et al. Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice. Nat Commun 13, 2464 (2022). https://doi.org/10.1038/s41467-022-30022-2

Guo Y, Al-Jibury E, Garcia-Millan R, Ntagiantas K, King JWD, Nash AJ, Galjart N, Lenhard B, Rueckert D, Fisher AG, Pruessner G, Merkenschlager M. Chromatin jets define the properties of cohesin-driven in vivo loop extrusion. Mol Cell. 2022 Oct 20;82(20):3769-3780.e5. doi: 10.1016/j.molcel.2022.09.003. Epub 2022 Sep 30. PMID: 36182691. https://pubmed.ncbi.nlm.nih.gov/36182691/

Robles-Rebollo, I., Cuartero, S., Canellas-Socias, A. et al. Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters. Nat Commun 13, 4342 (2022). https://doi.org/10.1038/s41467-022-31192-9

Calderon L, Weiss FD, Beagan JA, Oliveira MS, Georgieva R, Wang YF, Carroll TS, Dharmalingam G, Gong W, Tossell K, de Paola V, Whilding C, Ungless MA, Fisher AG, Phillips-Cremins JE, Merkenschlager M. Cohesin-dependence of neuronal gene expression relates to chromatin loop length. Elife. 2022 Apr 26;11:e76539. doi: 10.7554/eLife.76539. PMID: 35471149; PMCID: PMC9106336.