About Us

The Epigenetic Memory Group study how information, that ultimately determines a cell's identity and function, is passed from one cell to another during cell division. While much is known about how DNA is replicated and inherited, we know less about how epigenetic information is transferred when cells divide. To understand this, our group focuses on defining the chromatin - DNA, proteins and RNAs - contained within mitotic chromosomes, and investigating how these influence chromosome structure and the gene expression patterns that are established as newly-formed daughter cells arise after cytokinesis.

The Epigenetic Memory Group are a small and highly collaborative team. We were established at Imperial College London/MRC LMS, but moved to the Biochemistry Department at the University of Oxford in 2023.

We are a multi-disciplined team with expertise that spans stem cell biology, immunology, development, chromosome biology, commitment, and reprogramming. We also pioneer the development of new methods - such as bioluminescence imaging of epigenetic changes in vivo, and using advanced flow cytometry and proteomics approaches to study mitotic bookmarking. We welcome collaborations with molecular, cellular and structural biologists interested in defining the properties of chromosomes and understanding how epigenetic mechanisms contribute to inheritance.